Perioperative Low-Dose Ketamine Infusion and its Impact on Postoperative Pain: An Evidence Based Practice Analysis
Repository Posting Date2018-05-31T20:37:01Z
Author(s)van den Hoven, Joseph Edward
TypeOther Graduate Paper
Level of EvidenceOther
Research ApproachTranslational Research/Evidence-based Practice
CINAHL HeadingsKetamine--Administration and Dosage; Postoperative Pain--Prevention and Control; Administration, Intravenous; Nursing Practice, Evidence-Based; Anesthesia Nursing; Ketamine; Postoperative Pain
Acute pain after surgery is a common problem with multiple consequences. Patients, anesthesia professionals, and surgeons want adequate pain control with minimal side effects. Opioid analgesics are commonly relied upon in the perioperative and postoperative periods to provide analgesia. Large doses of opioids are associated with sedation, respiratory depression, pruritus, nausea, vomiting, and potentially opioid induced hyperalgesia (OIH).1 The use of multimodal analgesia targeted at different pain mechanisms both peripherally and centrally has been reported to decrease pain and reduce opioid consumption.