Incorporating Dexamethasone with Local Anesthetics in Single-shot Nerve Blocks: An Integrative Review
Kyle G. Hilsabeck, BSN, RN
- Sigma Affiliation
Visits vs Downloads
Visitors - World Map
Top Visiting Countries
Top Visiting Cities
Visits (last 6 months)
Downloads (last 6 months)
Popular Works for Hilsabeck, Kyle G. by View
Popular Works for Hilsabeck, Kyle G. by Download
Prolonging the duration of analgesia in single-shot nerve blocks (SNBs) continues to be a problem in regional anesthesia. Both IV and perineural dexamethasone have proven to be effective in prolonging the duration of analgesia in SNBs.
Objective: The purpose of this integrative review was to determine how IV and perineural dexamethasone effect duration of analgesia, pain scores, opioid consumption, and complications in patients undergoing SNB.
Methods: An integrative review that included 12 peer-reviewed randomized-controlled trials (RCTs) and one meta-analysis was performed.
Results: The results of the integrative review found that perineural dexamethasone prolonged the duration of analgesia, reduced pain scores, and reduced opioid consumption to a greater extent than IV dexamethasone. IV dexamethasone prolonged the duration of analgesia to a greater extent than local anesthetic with saline and local anesthetic alone. There were no major complications associated with the use of dexamethasone in SNBs.
Conclusions: Perineural dexamethasone is a more effective adjunct in prolonging the duration of analgesia in SNBs compared to IV dexamethasone. IV dexamethasone is an effective, alternative adjunct that can be used to prolong the duration of analgesia in SNBs.
|Other Graduate Paper||Proxy-submission||Faculty Approved: Degree-based Submission||Text-based Document|
|Level of Evidence||Research Approach||Keywords||CINAHL Subject(s)|
|Literature Review||Translational Research/Evidence-based Practice||intravenous dexamethasone; |
single-shot nerve block;
peripheral nerve block;
|Dexamethasone--Administration and Dosage;
All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.
All permission requests should be directed accordingly and not to the Sigma Repository.
All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.