Ondansetron Administration Prior to Subarachnoid Block in Cesarean Section: An Evidence Based Practice Analysis
View File(s)
Subarachnoid block (SAB) is a preferred regional technique utilized by many institutions for caesarean section. A sensory block height of T5 is necessary for a successful caesarean under SAB. Unfortunately, side effects often emerge related to the physiological changes as a result of sympathetic nervous system inhibition. Current research suggests up to 55%-90% of parturients experience extended block height resulting in hypotension and bradycardia.There is a reduction in cardiac output due to a decrease in systemic vascular resistance and venous pooling. Similarly, the shift of cardiac autonomic balance toward parasympathetic stimulation causes bradycardia and activation of left ventricular mechanoreceptors due to a decreased ventricular volume. The mechanism is known as the Bezold-Jarisch reflex (BJR).
| Type | Other Graduate Paper |
| Acquisition | Proxy-submission |
| Review Type | Faculty Approved: Degree-based Submission |
| Format | Text-based Document |
| Evidence Level | N/A |
| Research Approach | N/A |
| Keywords | Bezold-Jarisch reflex; bradycardia; Cesarean Section; hypotension; ondansetron; subarachnoid block |
| CINAHL Subject(s) | Cesarean Section; Ondansetron--Administration and Dosage; Hypotension--Etiology; Anesthesia, Spinal--Adverse Effects--In Pregnancy; Reflex; Ondansetron; Hypotension; Anesthesia, Spinal--Adverse Effects; Anesthesia, Spinal |
| Grantor | Bryan College of Health Sciences |
| Advisor | Hadenfeldt, Sharon |
| Level | Doctoral – Other |
| Year | 2017 |
All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.
All permission requests should be directed accordingly and not to the Sigma Repository.
All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.
License
The following license files are associated with this item:
