Ondansetron Administration Prior to Subarachnoid Block in Cesarean Section: An Evidence Based Practice Analysis
Jeremy Bustamante, DNAP, CRNA
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Subarachnoid block (SAB) is a preferred regional technique utilized by many institutions for caesarean section. A sensory block height of T5 is necessary for a successful caesarean under SAB. Unfortunately, side effects often emerge related to the physiological changes as a result of sympathetic nervous system inhibition. Current research suggests up to 55%-90% of parturients experience extended block height resulting in hypotension and bradycardia.There is a reduction in cardiac output due to a decrease in systemic vascular resistance and venous pooling. Similarly, the shift of cardiac autonomic balance toward parasympathetic stimulation causes bradycardia and activation of left ventricular mechanoreceptors due to a decreased ventricular volume. The mechanism is known as the Bezold-Jarisch reflex (BJR).
|Type||Other Graduate Paper|
|Review Type||Faculty Approved: Degree-based Submission|
|CINAHL Subject(s)||Cesarean Section;
Ondansetron--Administration and Dosage;
Anesthesia, Spinal--Adverse Effects--In Pregnancy;
Anesthesia, Spinal--Adverse Effects;
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