Effects of dexmedetomidine on postoperative delirium in the older adult population undergoing cardiothoracic surgery: An evidence-based practice analysis
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A PICO question was developed to provide guidance for the research/literature review process. “In the greater than 60-year-old adult population undergoing cardiac or thoracic surgery with general anesthesia (P), does the use of intraoperative dexmedetomidine (I) affect the incidence of postoperative delirium (O) when compared to placebo (C)?” A literature search was conducted and completed by searching the following databases: PubMed, Scopus, MEDLINE Complete, Cumulative Index of Nursing and Allied Health Literature (CINAHL), and Academic Search Elite. Keywords used in the search strategy include dexmedetomidine, postoperative delirium, adult, geriatric, cardiopulmonary surgery, and thoracic surgery. Inclusion criteria were studies published in the last 10 years in a peer review journal, published in English, and full text. Included were studies that explored the relationship between intraoperative use of dexmedetomidine and postoperative delirium in older adults undergoing cardiac or thoracic surgery as a primary outcome. The search method yielded 133 results and of those, eight randomized-controlled trials (RCTs) were selected based on the inclusion criteria.
| Type | Other Graduate Paper |
| Acquisition | Proxy-submission |
| Review Type | Faculty Approved: Degree-based Submission |
| Format | Text-based Document |
| Evidence Level | Literature Review |
| Research Approach | Translational Research/Evidence-based Practice |
| Keywords | Postoperative Delirium; Dexmedetomidine; Older Adults; Cardiac Surgery; Thoracic Surgery |
| Grantor | Bryan College of Health Sciences |
| Advisor | Chandler, Holly |
| Level | Doctoral-Other |
| Year | 2023 |
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