An integrative review: The incidence of transient neurologic symptoms with the administration of intrathecal lidocaine or bupivacaine
View File(s)
Aims and Objectives: The aim of this integrative review is to analyze the effects of intrathecal administration of lidocaine and bupivacaine on transient neurologic symptoms (TNS).
Methods: A review of the literature was performed utilizing the following electronic databases: Ebsco, Medline, Pubmed, CINAHL Complete, and Cochrane Complete. Search results were critically appraised based on study method and design that aligned with this integrative review’s guiding questions.
Results: The use of lidocaine is associated with an increased risk of TNS when compared to other local intrathecal medications. The specific etiology of TNS remains unknown. This review revealed several contributing factors to the development of TNS. These factors include dosage and concentration of local medication, patient positioning, the type of needle used with intrathecal medication administration, and onset of ambulation after spinal anesthesia.
Conclusions: Intrathecal lidocaine is associated with an increased risk of TNS when compared to bupivacaine. Bupivacaine has a lower associated risk of TNS. Bupivacaine’s drug profile, when compared to lidocaine, is correlated with longer motor recovery, increased incidence of urinary retention, and delayed discharge times. These factors are undesirable in a fast-paced, quick turnover environment.
| Type | Other Graduate Paper |
| Acquisition | Proxy-submission |
| Review Type | Faculty Approved: Degree-based Submission |
| Format | Text-based Document |
| Evidence Level | Literature Review |
| Research Approach | Translational Research/Evidence-based Practice |
| Keywords | Transient Neurologic Symptoms; Intrathecal Anesthesia; Spinal Anesthesia; Lidocaine; Bupivacaine |
| Grantor | Bryan College of Health Sciences |
| Advisor | Pecka, Shannon |
| Level | Doctoral-Other |
| Year | 2023 |
All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.
All permission requests should be directed accordingly and not to the Sigma Repository.
All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.
License
The following license files are associated with this item:
Related items
Showing items related by title, author, creator and subjects.
-
Mepivacaine and bupivacaine spinal comparisons for motor function return, discharge time, and transient neurologic symptoms: An evidence based practice analysis
Bupivacaine is the most common local anesthetic used in spinals for total knee arthroplasty (TKA) and total hip arthroplasty (THA) procedures, despite its extended duration (3-9 hours). Most TKA's can be completed in ... -
Efficacy of pre-procedural ultrasound in facilitating neuraxial anesthetics: An integrative review
(2017-06-26)The purpose of this integrative review is to investigate the efficacy of pre-procedural ultrasound examination to facilitate neuraxial anesthesia techniques and its impact on first attempt success rates, number of attempts ... -
Neuraxial anesthesia’s role in external cephalic version: An integrative review
Background: External cephalic versions (ECVs) are used to move a fetus from breech position into a vertex position to allow for safer vaginal delivery. Neuraxial anesthesia has been studied as a method of pain control and ... -
The safety and efficacy of liposomal Bupivacaine administration in patients undergoing shoulder arthroplasty: An integrative review
The aim of this integrative review is to examine and report current evidence regarding the safety and efficacy of liposomal bupivacaine (LB) administration for post-operative analgesia in shoulder arthroplasty. The two ... -
Clonidine as an adjunct to intrathecal bupivacaine: An integrative review
Aims and objectives: The aim of this integrative review is to provide current, evidence-based anesthetic recommendations for the use of clonidine as an adjuvant to bupivacaine for patients undergoing total knee arthroplasty ...
