Investigating chemobrain onset: A pilot study exploring the severity and onset of cognitive impairment
View File(s)
- Author(s)
- Details
-
Kelly Moore, BSN, RN, OCN, email: Kelly2.Moore@UTSouthwestern.edu. Ms. Moore has been a Registered Nurse since 2010. Since then she has worked with oncology patients in the capacity as a bedside nurse, infusion nurse, and as a nurse manager. She is a member of the American Nurses Association, Texas Nurses Association, and Oncology Nurses Association. She served as the Principal Investigator of The Chemobrain Study, which was a multi-center study that was funded by the J. Patrick Barnes research grant. Daiwai Olson, PhD, RN, CCRN, email: Daiwai.Olson@UTSouthwestern.edu.
- Sigma Affiliation
- Non-member
- Contributor Affiliation(s)
- The University of Texas Southwestern Medical Center, Dallas, Texas, USA
Visitor Statistics
Visits vs Downloads
Visitors - World Map
Top Visiting Countries
Country | Visits |
---|
Top Visiting Cities
City | Visits |
---|
Visits (last 6 months)
Downloads (last 6 months)
Popular Works for Moore, Kelly by View
Title | Page Views |
---|
Popular Works for Moore, Kelly by Download
Title | Downloads |
---|
View Citations
Citations
Background: Chemotherapy related changes in cognition fall into a cluster of symptoms commonly referred to as chemobrain. To date, nursing literature on the progression of chemobrain and tools used to describe this progression are scant.
Objectives: The purpose of this pilot study was to explore the onset of chemobrain in persons who recently began chemotherapy and those who have been undergoing therapy for a longer period of time.
Methods: This was a prospective, non-randomized, observational, pilot feasibility study of adult chemotherapy patients pilot that aimed to provide a foundation into nursing research examining cognitive changes associated with chemotherapy.
Findings: Of 50 subjects enrolled 16 had lower scores at follow-up and 14 had improved scores comparing baseline and follow-up. According to the Trail Making A&B testing, 49 of 50 patients fell in the healthy range of cognitive functioning. Paired t-tests showed significant differences in baseline and 8-month Trail Making A scores (p<0.05), and comparing 4 and 8-month Trail Making B score (p<0.05). The mixed results suggest that Trail Making A & B may not be appropriate tests for chemotherapy associated cognitive decline in patients (chemobrain).
The research study is completed. At the time of submission to this repository, a manuscript was under review with the Clinical Journal of Oncology Nursing.
Type | Poster |
Acquisition | Self-submission |
Review Type | Abstract Review Only: Reviewed by Event Host |
Format | Text-based Document |
Evidence Level | Observational |
Research Approach | Pilot/Exploratory Study |
Keywords | Chemotherapy; Cognitive Functioning; Nursing |
CINAHL Subject(s) | Cognition--Drug Effects; Chemotherapy, Cancer--Adverse Effects; Oncologic Nursing; Cognition; Chemotherapy, Cancer |
Name | Oncology Nursing Society |
Host | Oncology Nursing Society |
Location | Anaheim, California, USA |
Date | 2019 |
All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.
All permission requests should be directed accordingly and not to the Sigma Repository.
All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.
Related items
Showing items related by title, author, creator and subjects.
-
Cognitive function in breast cancer patients undergoing chemotherapy
Jansen, Catherine E.Background. Recent studies suggest that standard dose chemotherapy (CTX) may cross the blood-brain barrier. However, the evidence for CTX-induced cognitive impairments in breast cancer patients is inconsistent. Purposes. ... -
Chemotherapy-related cognitive impairment: The breast cancer experience
Myers, Jamie S.The aims of this qualitative descriptive study were to describe the experience of chemotherapy-related cognitive impairment (CRCI) for women with breast cancer who received chemotherapy; and identify information about CRCI ... -
Effects of virtual reality on symptom distress in children receiving cancer chemotherapy
Schneider, Susan M.The objective of this study was to test the premise that virtual reality, as a developmentally appropriate distraction intervention, mitigates chemotherapy related symptom distress in older children with cancer aged 10-17. ... -
The experience of cognitive change in women with breast cancer following chemotherapy
Kanaskie, Mary LouiseBackground: Change in cognitive function is one side effect of chemotherapy that has been reported in some breast cancer survivors. Alarming reports indicate that between 16 to 50 percent of women receiving chemotherapy ... -
Depression, balance, and cognitive function in the elderly that practice and do not practice yoga: A comparative study
Gonzalez, Hermes; Villarreal-Reyna, Maria de los Angeles; Arredondo, Ana Maria; Molina, Wendy (2014-11-17)Session presented on Saturday, July 26, 2014: Purpose: To identify the relationship between the levels of depression, balance problems, and cognitive impairment in Mexican elderly that practice and do not practice ...